Vacancy for a highly motivated postdoctoral researcher: “Investigating the metabolic effects of permeation enhancers on in vitro model systems by metabolomics and lipidomics”

For a collaborative project between Johnson & Johnson and the University of Leuven (KU Leuven), focusing on the investigation of the mode of action and potential adverse effects of permeation enhancers for application in beyond-rule-of-5 (bRO5) therapeutics, the Advanced Material Characterization & Investigations team within Analytical Development (AD-AMCI) of Johnson & Johnson Innovative Medicine (JJIM) and the division of Pharmaceutical Analysis of the Department of Pharmaceutical and Pharmacological Sciences of KU Leuven are looking for a highly motivated postdoctoral researcher.

AD-AMCI is an international and diverse multidisciplinary team of scientists leading advanced characterization and increasing mechanistical understanding of drug substances and drug products. We are also leading analytical investigations for the commercial and R&D portfolio. Within AMCI, the Advanced Molecular Analysis (AMA) team is a group of analytical centers of excellence in structure elucidation (by High-Resolution Mass Spectrometry and NMR), trace organic analysis, excipient & polymer characterization, etc.

Within Pharmaceutical Analysis, the research group of Prof. Deirdre Cabooter is working on the fundamental investigation of mass transfer phenomena in liquid chromatography, the implementation of multidimensional liquid chromatography (LC) techniques in combination with mass spectrometry (MS) for applications in different fields of research (environmental, pharmaceutical, biological) and the development of automatable method development strategies for complex samples.

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Responsibilities

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• The applicant ideally has a PhD in (Analytical) Chemistry, Pharmacy, Biomedical Sciences, (Bio-) Engineering, or equivalent, with a strong interest in analytical chemistry and metabolomics. 
• A good knowledge of and hands-on experience with liquid chromatography (LC) and mass spectrometry (MS), preferably for metabolomics/lipidomics analyses, are an absolute must. 
• Knowledge of and practical experience with two-dimensional LC are a plus. 
• Ideally, the applicant should also have hands-on experience working with cell cultures. 
• The applicant is familiar with the management, analysis and interpretation of complex datasets. 
• Candidates must be proficient in oral and written English, must have excellent communication skills, multi-tasking skills, and be team-oriented, proactive and results driven. 

The position will start on September 1st, 2024. Interested candidates should send their CV and a motivation letter using the KU Leuven online application tool.

Offer

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• We offer a postdoctoral research position in a stimulating environment, wherein you will work in an internationally reputed pharmaceutical company with a strong focus on R&D, in a well-equipped, experienced and internationally oriented research unit. 
• Your main workplace will be at the Johnson & Johnson Innovative Medicine site in Beerse, Belgium. 
• Frequent meetings and discussions (both online and live) will be organized with the academic promoter in Leuven. 
• Some of the experimental work can also be executed in the lab of the academic supervisor, situated at the Gasthuisberg campus in Leuven.

Interested?

For more information please contact Prof. dr. Deirdre Cabooter, tel.: +32 16 32 34 42, mail: deirdre.cabooter@kuleuven.be.

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