Postdoc in computational biophysics

Job description

Ion channels are essential for life across organisms and a sophisticated understanding of their function is imperative for basic, biomedical and applied research. The overarching goal of the proposed project is to develop ion channel activators and inhibitors. Previously unmet specificity needs will be achieved by targeting subtype- and conformational-specific features, thereby limiting side effects. The focus will be on Kv7 channels linked to a range of severe neurological disorders, including epilepsy, sleep disorders and autism.

The postdoc will carry out molecular dynamics simulations of these channels bound to various modulators, and integrate the results within a collaborative project with four other principal investigators carrying out cryo-electron microscopy, electrophysiology, behavioral experiments and machine learning.

What we offer

• A position at a leading technical university that generates knowledge and skills for a sustainable future
• Engaged and ambitious colleagues along with a creative, international and dynamic working environment
• Work in Stockholm, in close proximity to nature
• Help to relocate and be settled in Sweden and at KTH

Read more about what it is like to work at KTH

Qualifications

Requirements

• A doctoral degree or an equivalent foreign degree. This eligibility requirement must be met no later than the time the employment decision is made.
• Experience with molecular dynamics simulations
• Experience working in collaborative work environments
• Research expertise
• Awareness of diversity and equal opportunity issues, with specific focus on gender equality
• Collaborative abilities
• Independence

Preferred qualifications

• A doctoral degree or an equivalent foreign degree, obtained within the last three years prior to the application deadline
• Teaching abilities
• Experience with Enhanced sampling simulations and coarse grained force fields
• Experience with biological systems including membrane proteins

Great emphasis will be placed on personal skills.

Trade union representatives

Contact information to trade union representatives.

To apply for the position

Log into KTH's recruitment system to apply for this position. You are responsible for ensuring that your application is complete according to the instructions in the ad.

The application must include:

• CV including relevant professional experience and knowledge.
• Brief account of why you want to conduct research, your academic interests and how they relate to your previous studies and future goals. Max two pages long.

Your complete application must be received at KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time).

About the employment

The position offered is for, at the most, two years.

A position as a postdoctoral fellow is a time-limited qualified appointment focusing mainly on research, intended as a first career step after a dissertation.

Others

Striving towards gender equality, diversity and equal conditions is both a question of quality for KTH and a given part of our values.

For information about processing of personal data in the recruitment process.

According to The Protective Security Act (2018-585), the candidate must undergo and pass security vetting if the position is placed in a security class. Information regarding whether the position is subject to such a classification will be provided during the recruitment process.

We firmly decline all contact with staffing and recruitment agencies and job ad salespersons.

Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence.

About KTH

KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy. Read more here

1. Lucie Delemotte, lucied@kth.se